Manuel Claudio arrived in Greenport aboard the Portuguese whaler Neve in 1854. Upon retirement in 1870, he established a saloon on lower Main Street. He later acquired the present property at the Main Street Wharf and opened the restaurant and a hotel. Claudio's quickly became an integral part of the Greenport harborscape and has been operated by the Claudio family ever since. The building, on the National Historic Register since 1945, has a two-story enclosed porch and paneled door entries with spindled brackets. Inside is an ornate mirrored bar that Manuel salvaged from a New York Bowery hotel and installed in 1886.